A.The issue of AMR led the scientists to be alert to the new human gene.
B.A new drug will be soon available for any multi-drug resistant bacteria.
C.A new strain has been found to be highly resistant to almost all antibiotics.
D.AMR aroused the awareness of the scientists to the infections caused by the antibiotics.
第1题
根据以下材料,回答题
Be Alert to Antimicrobial (抗菌剂) Resistance
The ability of micro-organisms to find ways to evade the action of the drugs used to cure the infections they cause is increasingly recognized as a global public health issue. Some bacteria have developed mechanisms which make them resistant to many of the antibiotics normally used for their treatment (multi-drug resistant bacteria), so pose particular difficulties, as there may be few or no alternative options for therapy. They constitute a growing and global publlic health problem.
WHO suggests that countries should be prepared to implement hospital infection control measures to limit the spread of multi-drug resistant strains and to reinforce national policy on prudent use of antibiotics, reducing the generation of antibiotic resistant bacteria.
An article punished in The Lancet Infectious Diseases on 11 August 2010 identified a new gene that enables some types of bacteria to be highly resistant to almost all antibiotics. The article "has drawn attention to the issue of AMR (antimicrobial resistance) and, in particular, has raised awareness of infections caused by multidrug resistant bacteria.
While multi-drug resistant bacteria are not new and will continue to appear, this development requires monitoring and further study to understand the extent and modes of transmission, and to define the most effective measures for control.
Those called upon to be alert to the problem of antimicrobial resistance and take appropriate action include consumers, managers of hospitals, patients, as well as national govemments, the pharmaceutical industry and intemational agencies.
WHO strongly recommends that governments focus control and prevention efforts in the following areas like surveillance for antimicrobial resistance; rational antibiotic use, including education of healthcare workers and the public in the appropriate use of antibiotics; introducing or enforcing legislation related to stopping the selling of antibiotics without prescription; and strict adherence to infection prevention and control measures, including the use of hand-washing measures, particularly in healthcare facilities.
Successful control of multidrug-resistant microorganisms has been documented in many countries, and the existing and well-known infection prevention and control measures can effectively reduce transmission of multi-drug resistant organisms if systematically implemented.
WHO will continue to support countries to develop relevant policies, and to coordinate international efforts to combat antimicrobial resistance. Antimicrobial resistance will be the theme of WHO"s World Health Day 2011.
Why is the use of antibiotics arousing globally increasing interest? 查看材料
A.The misuse of the antibiotics has caused stronger bacteria resistance and no new drugs against the bacteria are available at present.
B.The micro-organisms develop much faster than the past, so the researchers are more interested.
C.The antibiotics for multi-drug resistant bacteria are highly priced and there will be a big market for the drug industry.
D.The antibiotics has been found more powerful for the treatment of the multi-drug resistant bacteria.
第2题
Paragraph 6 __________. 查看材料
A.Kripke"s research tool
B.Dangers of habitual shortages of sleep
C.Criticism on Kripke"s report
D.A way of overcoming insomnia
E.Sleep problems of long and short sleepers
F.Classification of sleep problems
第3题
Paragraph 5 __________. 查看材料
A.Kripke"s research tool
B.Dangers of habitual shortages of sleep
C.Criticism on Kripke"s report
D.A way of overcoming insomnia
E.Sleep problems of long and short sleepers
F.Classification of sleep problems
第4题
Paragraph 4 __________. 查看材料
A.Kripke"s research tool
B.Dangers of habitual shortages of sleep
C.Criticism on Kripke"s report
D.A way of overcoming insomnia
E.Sleep problems of long and short sleepers
F.Classification of sleep problems
第5题
根据以下材料,回答题
More Than 8 Hours" Sleep
Although the dangers of too little sleep are widely known, new research suggests that people who sleep too much may also suffer the consequences.
Investigators at the University of California in San Diego found that people who clock up 9 or 10 hours each weeknight appear to have more trouble falling and staying asleep, as well as a number of other sleep problems, than people who sleep 8 hours a night. People who slept only 7 hours each night also said they had more trouble falling asleep and feeling refreshed after a night"s sleep than 8-hour sleepers.
These findings, which DL Daniel Kripke reported in the journal Psychosomatic Medicine,demonstrate that people who want to get a good night"s rest may not need to set aside more than 8 hours a night. He added that "it might be a good idea" for people who sleep more than 8 hours each night to consider reducing the amount of time they spend in bed, but cautioned that more research is needed to confirm this.
Previous studies have shown the potential dangers of chronic shortages of sleep—— for instance,one report demonstrated that people who habitually sleep less than 7 hours each night have a higher risk of dying within a fixed period than people who sleep more.
For the current report, Kripke reviewed the responses of 1,004 adults to sleep questionnaires,in which participants indicated how much they slept during the week and whether they experienced any sleep problems. Sleep problems included waking in the middle of the night, arising early in the morning and being unable to fall back to sleep, and having fatigue interfere with day-to-day functioning.
Kripke found that people who slept between 9 and 10 hours each night were more likely to report experiencing each sleep problem than people who slept 8 hours. In an interview, Kripke noted that long sleepers may struggle to get rest at night simply because they spend too much time in bed. As evidence, he added that one way to help insomnia is to spend less time in bed. "It stands to reason that if a person spends too long a time in bed, then they"ll spend a higher percentage of time awake." he said.
Paragraph 2 __________. 查看材料
A.Kripke"s research tool
B.Dangers of habitual shortages of sleep
C.Criticism on Kripke"s report
D.A way of overcoming insomnia
E.Sleep problems of long and short sleepers
F.Classification of sleep problems
第6题
根据以下材料,回答题
Cancer Drug Trials Often Halted Early
An increasing number of clinical trials for new cancer treatments are being halted before the risks and benefits have been fully evaluated, say Italian researchers, who warn that this growing trend could put patients at risk of harm from new therapies rushed into use.
The researchers looked at 25 randomized, controlled clinical trials that were stopped early because the treatments had started to show benefit to patients.
"When we analyzed 25 trials over a 10-year period between 1997 and 2007, we found a consistent increase in prematurely stopped trials——more than 50 percent were stopped within the last three years," study co-author Giovanni Apolone said at a news conference Tuesday.
Of 14 trials halted early and published between 2005 and 2007, the researchers found that 11(79 percent) of them were used to support drug approval applications submitted to the European Medicines Agency and the U.S. Food and Drug Administration.
"This suggests a strong commercial component in stopping trials prematurely. In fact, this strategy could guarantee quicker access to the market for companies. On the other hand, a quicker clinical drug development may lead to an "immature" benefit/risk balance of new drugs,"Apolone said.
He and his colleagues "are aware that trials stopped early because they are showing benefit may result in identification of promising new treatments for patients. However, findings obtained following this strategy should be considered to be preliminary results that require subsequent confmnation."
It can take several years for the long-term benefits or harmful side effects of a new treatment to become apparent, Apolone noted, but the average duration (持续时间) of the 25 studies he and his colleagues analyzed was 30 months, with a range from 12 to 64 months.
They also found that at the time five of the studies were stopped, they"d enrolled less than 40 percent of the total number of patients planned for final analysis.
"Clinical trials need to stop early for superior benefit whenever there"s proof beyond reasonable doubt that the new treatment really is superior. That would be an ethical obligation,"Stuart Pocock, a professor of medical statistics at the London School of Hygiene and Tropical Medicine in the United Kingdom, said at the news conference. "However, too many trials are stopped early claiming efficacy (功效) without strong evidence being available."
The number of prematurely stopped clinical trials has increased recently. 查看材料
A.Right
B.Wrong
C.Not mentioned
第7题
Mary said mildly, "I‘m just curious about it."
A.gently
B.shyly
C.weakly
D.sweetly
第8题
He has interest in various domains.
A.extents
B.zones
C.fields
D.regions
第9题
There are fierce competitions among these companies.
A.intense
B.various
C.eager
D.diverse
第10题
I extracted several interesting sentences from this passage.
A.take out
B.take off
C.take in
D.take up
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